diff -up OpenCV-2.1.0/CMakeLists.txt.rpath OpenCV-2.1.0/CMakeLists.txt
--- OpenCV-2.1.0/CMakeLists.txt.rpath	2010-06-25 17:13:42.000000000 +0200
+++ OpenCV-2.1.0/CMakeLists.txt	2010-06-25 17:13:55.000000000 +0200
@@ -13,7 +13,7 @@ set(CMAKE_ALLOW_LOOSE_LOOP_CONSTRUCTS tr
 # Add these standard paths to the search paths for FIND_LIBRARY
 # to find libraries from these locations first
 if(UNIX)
-  set(CMAKE_LIBRARY_PATH ${CMAKE_LIBRARY_PATH} /lib /usr/lib)
+  set(CMAKE_LIBRARY_PATH ${CMAKE_LIBRARY_PATH} /lib /lib64 /usr/lib /usr/lib64)
 endif()
 # it _must_ go before PROJECT(OpenCV) in order to work
 if (NOT CMAKE_INSTALL_PREFIX)